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Figure 4: (a) Desmoplastic medulloblastoma, histologic and immunohistochemical features. (a) Note nodules of rounded, primitive neoplastic cells (H and E, ×200). (b) Note reticulin-free nodules encircled by reticulin-rich zones (Reticulin, ×200). (c) Note weak immunoreactivity of neoplastic cells for NSE (IHC, ×200). (d) Note extensive nuclear staining of neoplastic cells for Ki67 (IHC, ×200)

Figure 4: (a) Desmoplastic medulloblastoma, histologic and immunohistochemical features. (a) Note nodules of rounded, primitive neoplastic cells (H and E, ×200). (b) Note reticulin-free nodules encircled by reticulin-rich zones (Reticulin, ×200). (c) Note weak immunoreactivity of neoplastic cells for NSE (IHC, ×200). (d) Note extensive nuclear staining of neoplastic cells for Ki67 (IHC, ×200)