Year : 2017 | Volume
: 5 | Issue : 2 | Page : 124--129
Morning blood pressure surge as a predictor of outcome in patients with essential hypertension
Mohamed Y Abdel-Khalik1, Shereen A Mahrous2, Alsayed A Shanab1, Abdullah M Alshehri3, Mustafa H Rashed1, Ayman M Azoz1
1 Department of Cardiac Technology, College of Applied Medical Sciences, Dammam, Saudi Arabia
2 Department of Family Medicine, Primary Health Care Center in Dammam, Ministry of Health, Saudi Arabia
3 Department of Cardiology, College of Medicine, University of Dammam, Dammam, Saudi Arabia
Objective: To determine the usefulness of monitoring morning blood pressure surge (MBPS) to predict cardiovascular events in patients with essential hypertension.
Materials and Methods: A total of 81 patients (43 males and 38 females) with a mean age of 55.9 ± 9.8 years with essential hypertension were included in the study. Twenty-four hour ambulatory blood pressure (BP) monitoring was carried out to record MBPS. All patients were followed up for 36 months for cardiovascular events.
Results: Mean MBPS was 26.23 ± 10.17 mmHg. Nineteen patients (23%) who experienced a cardiovascular event during the follow-up period had higher MBPS than patients who did not experience a cardiovascular event (P < 0.0001). MBPS was positively correlated with interventricular septum thickness (r = +0.38 and P = 0.000), left atrial size (r = +0.39 and P = 0.000), 24-h mean systolic BP (r = +0.36 and P = 0.001) and total cholesterol level (r = +0.23 and P = 0.003). MBPS was negatively correlated with high-density lipoprotein-cholesterol (r = −0.37 and P = 0.001).
Conclusion: MBPS can be used as a biomarker for a cardiovascular disease event in hypertensive patients.
Mohamed Y Abdel-Khalik
King Abdulaziz Street, Alzohoor Neighborhood, P.O. Box 1982, Dammam 31441
|How to cite this article:|
Abdel-Khalik MY, Mahrous SA, Shanab AA, Alshehri AM, Rashed MH, Azoz AM. Morning blood pressure surge as a predictor of outcome in patients with essential hypertension.Saudi J Med Med Sci 2017;5:124-129
|How to cite this URL:|
Abdel-Khalik MY, Mahrous SA, Shanab AA, Alshehri AM, Rashed MH, Azoz AM. Morning blood pressure surge as a predictor of outcome in patients with essential hypertension. Saudi J Med Med Sci [serial online] 2017 [cited 2021 Apr 20 ];5:124-129
Available from: https://www.sjmms.net/article.asp?issn=1658-631X;year=2017;volume=5;issue=2;spage=124;epage=129;aulast=Abdel-Khalik;type=0