Year : 2013 | Volume
: 1 | Issue : 2 | Page : 94--97
Epidemiology and outcome of congenital diaphragmatic hernia in a tertiary care university hospital: 10 Years«SQ» Experience
Hatim K Al-Turkistani
Department of Pediatrics, King Fahd Hospital of the University, Al-Khobar, College of Medicine, University of Dammam, Saudi Arabia
Background: Congenital diaphragmatic hernia (CDH) is a major birth defect, which continues to be associated with significant rate of morbidity and mortality. CDH-local studies are limited. The objective of this article is to determine the epidemiology and demographics of CDH; and if the introduction of nitric oxide has influenced the outcome.
Materials and Methods: A retrospective 10-year medical records review of neonates with CDH admitted to the neonatal intensive care unit (NICU) of a tertiary care hospital.
Results: A total of 29 infants had been admitted to the NICU with CDH between January 2001 and December 2010. The mean gestational age was 38.58 2.6 weeks and the mean birth weight was 2821 682 g. The incidence of CDH among the inborn infants was 1/250 live births (P < 0.05) and the overall male to female ratio was 0.7. Of the 12 infants (41%) were inborn and 17 (59%) were referred from other centers. Out of the 29 infants, 23 (79%) were Saudis; the same figure was true for the vaginal deliveries and those born at term. Only 10 infants (34%) were diagnosed antenatally. The mean Apgar scores were 5 and 7 at the 1 st and 5 th min respectively. Two infants (7%) had right-sided defect against 27 (93%) who had it left-sided. Moreover, 18 infants had survived and were discharged home, with an overall mortality rate of 38% (compared with 45% before introducing inhaled nitric oxide [iNO]), P > 0.05.
Conclusion: The incidence of CDH was found much higher than the reported cases in literature; and although the mortality rate has improved after the introduction of iNO, the difference was not statistically significant. Both interesting findings necessitate further studies.
Hatim K Al-Turkistani
Department of Pediatrics, King Fahd Hospital of the University, Al-Khobar, P.O. Box 2208, Al-Khobar 31952
|How to cite this article:|
Al-Turkistani HK. Epidemiology and outcome of congenital diaphragmatic hernia in a tertiary care university hospital: 10 Years' Experience.Saudi J Med Med Sci 2013;1:94-97
|How to cite this URL:|
Al-Turkistani HK. Epidemiology and outcome of congenital diaphragmatic hernia in a tertiary care university hospital: 10 Years' Experience. Saudi J Med Med Sci [serial online] 2013 [cited 2020 Dec 4 ];1:94-97
Available from: https://www.sjmms.net/article.asp?issn=1658-631X;year=2013;volume=1;issue=2;spage=94;epage=97;aulast=Al-Turkistani;type=0