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CASE REPORT
Year : 2021  |  Volume : 9  |  Issue : 2  |  Page : 195-198

FDG PET/CT in the evaluation of a rare case of multisystem involvement in newly diagnosed Rosai–Dorfman–Destombes disease


1 Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
2 Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
3 Department of Pathology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

Correspondence Address:
Ahmed Fathala
Department of Radiology, Medical Imaging Service, King Faisal Specialist Hospital and Research Center, MBC#28 P. O Box 3354, Riyadh
Saudi Arabia
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DOI: 10.4103/sjmms.sjmms_99_20

PMID: 34084112

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Rosai–Dorfman–Destombes disease (RDD) is a rare histocytic disorder with a broad spectrum of clinical presentations. The disease typically presents with lymphadenopathy but may involve multiple systems. Usually, RDD lesions demonstrate intense [18]F-Fluorodeoxyglucose (FDG) uptake in positron emission tomography/computed tomography (PET/CT) imaging due to the inflammation and infiltration with high metabolic process of the disease. Here, we describe a rare case of 37-year-old man who presented with multiple systemic symptoms, including fever, weight loss and bilateral cervical, and inguinal lymphadenopathy who underwent FDG PET/CT for detection of disease extension. This case highlights the role of FDG PET/CT in establishing the disease extent in newly diagnosed RDD and guiding the therapeutic recommendations and for follow-up to monitor the disease response to therapy. To the best of our knowledge, this is the first case report from Saudi Arabia highlighting the role of FDG PET/CT in newly diagnosed RDD.


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