Home Print this page Email this page Users Online: 336
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2021  |  Volume : 9  |  Issue : 1  |  Page : 10-15

Understanding Obesity: The Role of Adipose Tissue Microenvironment and the Gut Microbiome

1 Department of Endocrinology and Diabetes, St. Vincent's University Hospital, Dublin, Ireland
2 Department of Endocrinology, St. Columcille's Hospital, Dublin, Ireland
3 Department of Endocrinology and Diabetes, Education and Research Centre, Obesity Immunology Group, University College Dublin, St. Vincent's University Hospital and St. Columcille's Hospital, Dublin, Ireland

Correspondence Address:
Dr. Nusrat M Awan
Department of Endocrinology and Diabetes, St. Vincent's University Hospital, Elm Park, Dublin
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sjmms.sjmms_561_20

Rights and Permissions

The prevalence of obesity has more than doubled globally over the past few decades, with a 12-fold rise in extreme levels. Obesity, with its multiple complications, remains a major ongoing challenge for health-care professionals, as highlighted by the COVID-19 pandemic, where people with obesity had poorer outcomes. In this article, we review advances in our understanding of the pathophysiology underlying obesity, with a focus on the immune system and its interaction with both the adipose tissue organ and the gut microbiome. As our understanding of the causes and effects of obesity improves, opportunities should emerge, underpinned by rigorous laboratory and clinical research, to both better prevent and treat this global epidemic.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded519    
    Comments [Add]    
    Cited by others 2    

Recommend this journal