Home Print this page Email this page Users Online: 9
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2020  |  Volume : 8  |  Issue : 1  |  Page : 25-31

Diagnostic accuracy of ultrasonography in classifying thyroid nodules compared with fine-needle aspiration


1 Radiology Department, King Fahd Hospital of the University, Al Khobar, Saudi Arabia
2 College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

Correspondence Address:
Dr Ibrahim Abobaker Al-Ghanimi
Department of Radiology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam
Saudi Arabia
Login to access the Email id

DOI: 10.4103/sjmms.sjmms_126_18

PMID: 31929775

Rights and Permissions

Background: Classifying thyroid lesions is challenging; nonetheless, using ultrasonography may allow for accurate diagnosis, differentiation and management of thyroid lesions and help avoid unnecessary biopsy. Objectives: The main objective of the study is to determine the diagnostic accuracy of ultrasonography in classifying thyroid nodules compared with fine-needle aspiration. Materials and Methods: This retrospective study included all 68 patients diagnosed with thyroid nodules at King Fahd Hospital of the University, Al Khobar, Saudi Arabia, between June 1, 2014, and November 30, 2016. Parameters were selected based on the Society of Radiologists in Ultrasound criteria. Ultrasonographic features, namely, nodule margins, echotexture, vascularity and calcifications, and fine-needle aspiration cytology (FNAC) results were reviewed by two radiologists blinded to each other's findings and validated by another experienced interventional radiologist. Ultrasonography results were compared against that of FNAC to calculate sensitivity and positive- and negative-likelihood ratios, and the nodule types were compared using Fisher's exact test. Results: Of the 68 nodules analyzed, 59 were reported as benign using FNAC (specificity = 95%; P &< 0.001). Of these 59, 56 were also reported as benign using ultrasonography. The specificity of ultrasonography in determining benign nodules was 94.9%, and the positive- and negative-likelihood ratios were 13.0 and 0.35, respectively. Six of the nine suspicious nodules were confirmed as malignant using FNAC, and the ultrasonography and FNAC findings were strongly associated (P = 0.001). According to the Society of Radiologists in Ultrasound criteria, FNAC and ultrasonography findings were significantly associated for nodule calcification (P = 0.001) and echogenicity (P = 0.001). Conclusion: The diagnostic specificity of ultrasonography and FNAC in this study are consistent with those reported previously, indicating that ultrasonography reliably classifies thyroid nodules, and thus can assist in the decision-making regarding need for biopsy.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1424    
    Printed100    
    Emailed0    
    PDF Downloaded285    
    Comments [Add]    

Recommend this journal