| REVIEW ARTICLE |
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| Year : 2017 | Volume
: 5
| Issue : 2 | Page : 93-103 |
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Vibrio Parahaemolyticus: A review on distribution, pathogenesis, virulence determinants and epidemiology
Lubna Ghenem1, Nasreldin Elhadi1, Faisal Alzahrani1, Mitsuaki Nishibuchi2
1 Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Dammam, 31441 Dammam, Kingdom of Saudi Arabia
2 Center for Southeast Asian Studies, Kyoto University, 46 Shomoadachi-cho, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan
Correspondence Address:
Nasreldin Elhadi
Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Dammam, P.O. Box 2435, 31441 Dammam
Kingdom of Saudi Arabia
 DOI: 10.4103/sjmms.sjmms_30_17 PMID: 30787765 
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Vibrio parahaemolyticus is a Gram-negative, halophilic bacterium isolated from marine environments globally. After the consumption of contaminated seafood, V. parahaemolyticus causes acute gastroenteritis. To initiate infection, a wide range of virulence factors are required. A complex group of genes is known to participate in the pathogenicity of V. parahaemolyticus; however, to understand the full mechanism of infection, extensive research is yet required. V. parahaemolyticus has become the leading cause of seafood-related gastroenteritis in Japan, the United States and several other parts of the world. In addition, outbreaks caused by the pandemic clone of this organism are escalating and spreading universally. To minimize the risk of V. parahaemolyticus infection and warrant the safety of seafood, collaboration between governments and scientists is required. We herein provide an updated review of the pathogenicity determinants and distribution of V. parahaemolyticus to deliver a better understanding of the significance of V. parahaemolyticus and its host–pathogen interactions. |
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