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Year : 2017  |  Volume : 5  |  Issue : 2  |  Page : 124-129

Morning blood pressure surge as a predictor of outcome in patients with essential hypertension

1 Department of Cardiac Technology, College of Applied Medical Sciences, Dammam, Saudi Arabia
2 Department of Family Medicine, Primary Health Care Center in Dammam, Ministry of Health, Saudi Arabia
3 Department of Cardiology, College of Medicine, University of Dammam, Dammam, Saudi Arabia

Correspondence Address:
Mohamed Y Abdel-Khalik
King Abdulaziz Street, Alzohoor Neighborhood, P.O. Box 1982, Dammam 31441
Saudi Arabia
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DOI: 10.4103/1658-631X.204854

PMID: 30787769

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Objective: To determine the usefulness of monitoring morning blood pressure surge (MBPS) to predict cardiovascular events in patients with essential hypertension. Materials and Methods: A total of 81 patients (43 males and 38 females) with a mean age of 55.9 ± 9.8 years with essential hypertension were included in the study. Twenty-four hour ambulatory blood pressure (BP) monitoring was carried out to record MBPS. All patients were followed up for 36 months for cardiovascular events. Results: Mean MBPS was 26.23 ± 10.17 mmHg. Nineteen patients (23%) who experienced a cardiovascular event during the follow-up period had higher MBPS than patients who did not experience a cardiovascular event (P < 0.0001). MBPS was positively correlated with interventricular septum thickness (r = +0.38 and P = 0.000), left atrial size (r = +0.39 and P = 0.000), 24-h mean systolic BP (r = +0.36 and P = 0.001) and total cholesterol level (r = +0.23 and P = 0.003). MBPS was negatively correlated with high-density lipoprotein-cholesterol (r = −0.37 and P = 0.001). Conclusion: MBPS can be used as a biomarker for a cardiovascular disease event in hypertensive patients.

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