Saudi Journal of Medicine and Medical Sciences

REVIEW ARTICLES
Year
: 2015  |  Volume : 3  |  Issue : 1  |  Page : 2--7

A review on the hypoglycemic effect of nigella sativa and thymoquinone


Abdullah O Bamosa 
 Department of Physiology, College of Medicine, University of Dammam, Dammam, Saudi Arabia

Correspondence Address:
Abdullah O Bamosa
P.O. Box 2114, Dammam 31451
Saudi Arabia

Nigella sativa (black seeds) is a very famous and popular herb used for centuries in many communities. N. sativa has been shown to possess therapeutic potential to many illnesses. Hypoglycemic effect of N. sativa has been studied extensively in the literature. This review gathered and analyzed the results reported in the literature related to the hypoglycemic effect of N. sativa. A search was done for N. sativa and black seeds as key words in PubMed and Google scholar databases. Published studies document a hypoglycemic effect of N. sativa in normal and diabetic animals and humans. Volatile oil and thymoquinone seem to be the most effective fractions of the seed in producing its hypoglycemic effect. The mechanism of N. sativa hypoglycemic effect is multifactorial including increasing insulin level, decreasing insulin resistance, stimulating β cells activity, direct insulin-like effect, and decreasing intestinal glucose absorption. Further, basic followed by clinical research to explore N. sativa ingredient responsible for its promising hypoglycemic effect is recommended.


How to cite this article:
Bamosa AO. A review on the hypoglycemic effect of nigella sativa and thymoquinone.Saudi J Med Med Sci 2015;3:2-7


How to cite this URL:
Bamosa AO. A review on the hypoglycemic effect of nigella sativa and thymoquinone. Saudi J Med Med Sci [serial online] 2015 [cited 2020 Aug 13 ];3:2-7
Available from: http://www.sjmms.net/article.asp?issn=1658-631X;year=2015;volume=3;issue=1;spage=2;epage=7;aulast=Bamosa;type=0