|Year : 2017 | Volume
| Issue : 1 | Page : 1
Zika virus: An emerging pathogen
Abdulaziz A Al-Quorain
Department of Internal Medicine, College of Medicine, University of Dammam, Dammam, Kingdom of Saudi Arabia
|Date of Web Publication||16-Nov-2016|
Abdulaziz A Al-Quorain
P. O. Box 40001, Al-Khobar 31952
Kingdom of Saudi Arabia
|How to cite this article:|
Al-Quorain AA. Zika virus: An emerging pathogen. Saudi J Med Med Sci 2017;5:1
Zika virus is a flavivirus, transmitted by mosquitoes, mainly Aedes Aegypti. The virus was first isolated in 1947 from a rhesus monkey in the Zika forest in Uganda, Africa with the first human infections reported in 1952 in Uganda, Tanzania, and Nigeria.,,
The geographic spread of the Zika virus has involved more than 52 countries worldwide., In 2014, it reached the Western Hemisphere and was detected in Brazil in 2015. In 2016, the Zika virus infection reached the United States and currently, it has been reported in North, Central and South America, Micronesia, the Caribbean and some Southeast Asian countries.,,
The transmission of the Zika virus to humans can occur through various modes, including blood transfusion, laboratory exposure, sexual contact, maternal-fetal transmission, and mosquitoes.,
The clinical presentation is usually asymptomatic in the majority of cases. However, when symptoms are present, they are usually mild and can include low-grade fever, arthralgia, rash, and conjunctivitis. Severe clinical manifestations, including microcephaly, have been described in infants and Guillain-Barre syndrome has been reported as a neurological complication., Although the Zika virus infection is mild in more than 80% of cases, further multicenter studies are required to improve the management of the infection.
In this issue, Professor Adel Al-Afaleq reviews the pathogenesis, transmission, clinical manifestation, diagnosis, management, and prevention of this virus.
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